About 30 results found for searched term "PT 1" (0.013 seconds)
Cat.No. | Name | Target |
---|---|---|
M1771 | PTC124 (Ataluren) | CFTR |
Ataluren | ||
Ataluren (PTC124) is a novel, orally available small molecular CFTR-G542X nonsense allele inhibitor. | ||
M2007 | Romidepsin (FK228) | HDAC |
FK228; ISTODAX; Depsipeptide; FR 901228; NSC 630176 | ||
Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended | ||
M2089 | Irinotecan Hydrochloride Trihydrate | Topoisomerase |
Campto, CPT-11 | ||
Irinotecan hydrochloride trihydrate is a potent inhibitor of DNA topoisomerase I. | ||
M2228 | Abitrexate (Methotrexate) | Antifolate |
Amethopterin; CL14377; WR19039 | ||
Abitrexate is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. | ||
M2701 | Fidaxomicin | Antibiotic |
OPT-80; PAR-101; Clostomicin B1; Tiacumicin B | ||
Fidaxomicin is a narrow spectrum macrocyclic antibiotic that inhibits RNA polymerase sigma subunit. | ||
M3002 | Scriptaid | HDAC |
Scriptide; GCK1026 | ||
Scriptaid is an inhibitor of HDAC. It shows a greater effect on acetylated H4 than H3. | ||
M3274 | Pentagastrin | Cholecystokinin Receptor |
Peptavlon; ICI-50123 | ||
Pentagastrin (ICI-50123) is a synthetic polypeptide that has effects like gastrin when given parenterally. | ||
M25394 | BPTF-IN-1 | Epigenetic Reader Domain |
compound AU1 | ||
BPTF-IN-1 (compound AU1) is a selective bromodomain and PHD finger containing transcription factor (BPTF) bromodomain inhibitor with a Kd of 2.8 μM. BPTF-IN-1 shows to be selective for BPTF over BRD4 bromodomain. | ||
M3881 | Tafluprost | Prostaglandin Receptor |
Taflotan, Zioptan, AFP-168, MK2452 | ||
Tafluprost is a fluorinated analog of prostaglandin F2-alpha and a PGF2alpha agonist that may be used in glaucoma-related studies. | ||
M1555 | Amyloid β-Peptide (1-42) human,TFA | Amyloid |
Aβ1-42; β-Amyloid (1-42) | ||
Amyloid β-Peptide (1-42) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease. | ||
M1333 | Talabostat mesylate | Dipeptidyl Peptidase |
BXCL701 mesylate; Val-boroPro mesylate; PT100 mesylate | ||
Talabostat mesylate (Val-boroPro mesylate; PT100 mesylate) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC50 < 4 nM; Ki = 0.18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM). | ||
M4465 | Irinotecan | Topoisomerase |
(+)-Irinotecan; CPT-11; VAL-413 | ||
Irinotecan is an inhibitor of Topoisomerase I, and is is activated by hydrolysis to SN-38 (the active metabolite of Irinotecan). | ||
M4972 | 3-Amino-5-mercapto-1,2,4-triazole | Plant growth regulators |
Amitrole (3-amino-1,2,4-triazole) is a widely used herbicide. | ||
M5102 | PTP1B-IN-2 | Phosphatase |
PTP1B-IN-2 is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM. | ||
M5360 | 2-Aminoheptane | Others |
Tuaminoheptanez, Tuamine, Heptamine, 1-Methylhexylamine, 2-Heptylamine | ||
2-Aminoheptane is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor. | ||
M5711 | Irinotecan hydrochloride | Topoisomerase |
CPT-11 HCl | ||
Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1. | ||
M6579 | Cerestat | Others |
Aptiganel; CNS-1102 | ||
Cerestat (also known as Aptiganel, CNS-1102) is a potent and noncompetitive NMDA receptor antagonist. | ||
M7173 | PT 1 | Others |
PT 1 is a aMPK activator. | ||
M9049 | MPTP HCl | Dopamine Receptor |
MPTP hydrochloride; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Hydrochloride | ||
MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. | ||
M9130 | LSN3154567 | NAMPT |
Nampt-IN-1 | ||
LSN3154567 (also known as Nampt-IN-1) is a potent and elective NAMPT inhibitor, inhibits purified NAMPT with an IC50 of 3.1 nM. | ||
M9427 | CU-CPT17e | TLR |
CU-CPT17e is a potent multi-Toll-like receptor (TLR) agonist, which activates TLR3, TLR8 and TLR9. | ||
M9567 | Leptin (116-130) mouse | Others |
LEP(116-130) mouse | ||
Leptin (116-130) mouse is a synthetic leptin peptide fragment. | ||
M9570 | PTP1B-IN-9 | Proteasome |
PTP1B-IN-9 is a ubiquitin-proteasome system (UPS)-stressor with anticancer activity. | ||
M10059 | Prolactin-Releasing Peptide (1-31) (human) | Peptides |
Prolactin-Releasing Peptide (1-31) (human) is a high affinity GPR10 ligand. | ||
M10063 | Bremelanotide Acetate | Melanocortin Receptor |
PT-141 Acetate | ||
Bremelanotide Acetate (PT-141 Acetate) is a peptide containing seven amino acids and is also a macrocyclic compound. In addition, Bremelanotide Acetate is an agonist of the melanocortin 4 receptor (MC4R). | ||
M10202 | 1-Thioglycerol | Others |
3-Mercapto-1,2-propanediol | ||
1-Thioglycerol, a derivatization reagent, is used to study the pH-sensitive photoluminescence of aqueous thiol-capped CdTe nanocrystals. | ||
M10247 | Nesiritide acetate | Peptides |
natriureticpeptide; BNP-32; 124584-08-3 | ||
Nesiritide acetate is an agonist of natriuretic peptide receptors (NPRs), with Kd values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. | ||
M10330 | Teriparatide acetate | Others |
hPTH (1-34) acetate; Parathar acetate | ||
Teriparatide acetate is a PHT agonist, with an IC50 of 2 nM in HEK293 cells. | ||
M10358 | C-Type Natriuretic Peptide (CNP) (1-22), human | Angiotensin Receptor |
CNP-22, human | ||
C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide. | ||
M10565 | Kisspeptin-10, human TFA | Peptides |
KP-10; Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 | ||
Kisspeptin-10, human TFA is a potent vasoconstrictor and inhibitor of angiogenesis, it acts as a tumor metastasis suppressor via its receptor GPR54. |
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